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Signs and SymptomsSigns and Symptoms Symptoms of scleroderma vary from patient to patient and range from mild to severe. Depending on the type, symptoms may develop rapidly or slowly over time. In most cases, the initial symptoms are Raynaud's syndrome (i.e., decreased blood flow to the extremities causing numbness, tingling, and burning) and swelling and puffiness in the fingers. As many as 95% of all patients with systemic sclerosis experience Raynaud's syndrome, which often is brought on by exposur...Read the full article
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