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Risk Factors and Causes

Post a new topicby contentuser on Wed Dec 19, 2007 8:34 pm



Risk Factors and Causes

The cause of ankylosing spondylitis is unknown, and the origin and development of the disease is not well understood. AS may result from a combination of genetic and environmental factors.


Ankylosing spondylitis is associated with an inherited antigen (cell marker) called HLA-B27, and more than 90% of patients with the disease also have this antigen. AS also is associated with inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease.
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